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This slide illustrates what happens with a screening test when it is applied to a population of 1000 people with a disease prevalence of 10%. The sensitivity is 95% and the specificity is 95%. These are very good characteristics for a screening test. The positive predictive value in this instance is 67.9% (95/140). Of a 140 people that test positive, 95 will truly have disease. The negative predictive value in this instance is 99.4% (855/860).