compounds are shown to be carcinogenic in animal experiments. Nitrite reacts with amines,
amides, and other proteins to form N-nitroso compounds in the stomach. Nitrate is
reduced to nitrite by bacteria in the mouth or achlorhydric stomach. Despite concerns from
experimental studies, epidemiologic studies have shown no
direct evidence for the role of N-nitroso compounds in human gastric
carcinogenesis. Dietary nitrate and nitrite derives from
vegetables and preserved meats, respectively.
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