||What is more surprising is the recent recognition of the
importance of pulse pressure. Thus Verdecchia and colleagues have studied office pulse
pressure and that measured by ambulatory blood pressure monitoring in over 2,000 subjects
in a study in Italy, and have demonstrated an extremely strong gradient of risk according
to deciles of pulse pressure, particularly that measured by ambulatory monitoring. Indeed,
in statistical models, pulse pressure may be more important than systolic and diastolic
blood pressure, replacing these in mathematical models.