next front |1 |2 |3 |4 |5 |6 |7 |8 |9 |10 |11 |12 |13 |14 |15 |16 |17 |18 |19 |20 |21 |22 |23 |24 |25 |26 |27 |28 |29 |30 |31 |32 |33 |34 |review

Picture and text from "Evidence Aggregates Against Alpha-synuclein in Varied Neurologic Disorders" by Richard Robinson.   Neurology Today, Vol 4 (1) 7-11,  2004. Dr.John Trojanowski: "What we think goes wrong is that when alpha-syneclein aggregates, it is disabled or taken out of action, and can't interact with vesicles" or other factors in the neuron, leading to a loss of function and then neurodegeneration.