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Infection in ewes and goats, occasionally cattle, is not commonly clinical unless the animals are pregnant. Can cause significant abortion in indivdual flocks (associated with focal necrotising placentitis) and congenital abnormalities in lambs. Classical outcome of in utero is the 'hairy shaker' lamb. This reflects the tropism of the virus (and the other pestiviruses for foetal lymphoid, skin and CNS tissues. 'Hairy shaker' lambs have hair rather than wool coats and CNS lesions often with hypomyelinogenesis and hypocerebellum. Often there is in utero growth retardation (IUGR) in skeletal tissues and some lambs are born weak and most do not thrive. Some are persistently infected with the virus (see below with BVDV notes).