Sakr has more than 15 years of cumulative experiences in high-level management of Science, Technology and Innovation; and served as Acting President of ASRT, Vice-President of ASRT, Executive Director of Science and Technology Development Fund (STDF), Head of Genetic Engineering and Biotechnology Institute National Research Centre (NRC), and Co-founding Director of Center of Scientific Excellence for Advanced Sciences (NRC).  Sakr obtained his PhD in Plant Biotechnology from Faculty of Science, Tanta University, Egypt, in 1995 (most of the experimental work was carried out in Pavia University, Italy) and professorship in Plant Biotechnology in 2006.

Sakr received the State Prize for Scientific Encouragement in Advanced Biotechnology (1999), National Research Center Prize for Scientific Encouragement in Biology (1998), National Research Center Prize for Scientific Excellence in Biotechnology (2009), and was chosen as the scholar of the year (2019) by the Association of Egyptian American Scholars. He has more than 130 publications, three books (in Arabic), three chapters in co-authored books (Springer), more than 10 postdoctoral fellowships in Germany, India, Italy and USA, and more than 10 national and international research grants before joining STI management in Egypt in 2007. Sakr is serving as Editor-in-Chief of the Journal of Genetic Engineering and Biotechnology (Elsevier/Springer) since 2010, and the Arab Journal of Scince, Technology and Innovation Policies since 2020. He is also serving as elected Vice-President of some International Organizations, such as SESAME, NAM, and the Secretary-General of Arab Association of Biotechnology, Federation of Arab Scientific Research Councils, Arab League. On the national level, Sakr was member of Board of Directions (BOD), Board of Trustees (BOT) and Councils of many universities and research institutions including, for example, Cairo, Tanta and King Salman International University, Zewail, E–JUST, NRC, SARTA, EPRI, ERI, ARC, ADP, and more.