If we go back to look at the costs of the health care system itself, ten years ago the estimate was that poor adherence accounted for 100 billion dollars of unnecessary costs to the health care system annually. Those dollars have inflated because we have not seen improvement in our abilities to assist patients to follow treatment regimens. Now those dollars are up closer to 140 or 150 billion dollars a year. That is close to the amount of dollars that cardiovascular disease contributes to helping the country.