The kinds of errors that we pick up with people include: not just failure to adopt the regimen or early stoppage of treatment but reduction in levels of treatment, such as exercising only once a week instead of three or four times a week; taking medication but frequently missing episodes of dosage; over treatment, and I think we see that in both the exercise arena and in the medication arena; considerable variability in the conduct of treatment, which is probably the most common problem that we find and at least for pharmaco-therapy it impacts the clinical outcome from the medication; considerable dosage interval errors, as when something needs to be taken in certain periods within a certain window apart from the other dose; and then just general performance errors. To take an extreme one, I'm reminded of a colleague who was studying patients who were taking inhaled medications for asthma. She was using an electronic monitor on patients that were prescribed three asthma doses, maybe every four hours. The prescription said to leave a minute or so between puffs, but patients were allowing only seconds as intervals and were not getting therapeutic benefits. They were having some considerable performance error in how they were using their inhaler. Those kinds of problems are not uncommon.