Princess Khadija was born on 2 May 1879, and was married to Prince Abbas – both descendants of Muhammad Ali Pasha – in 1895.
One of the main buildings named after Princess Khadija was the palace built especially for her in Helwan in 1895. The palace was close to the saray of her mother, Amina Hanem, granddaughter of Abbas I of Egypt.
In 1902, Princess Khadija donated the Palace to the Ministry of Health to be a Pulmonology hospital. The Palace later served as the headquarters of the municipality of Helwan.
Under the protocol signed between Cairo Governorate and the Bibliotheca Alexandrina (BA), the Palace was renovated to become a new beacon of knowledge and contribute to the cultural life in a way similar to the BA.