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When they are used consistently and correctly, male and female condoms are the most effective methods in preventing HIV transmission and transmission of most STIs, as well as acquisition of these infections.

Clients should be instructed in proper use. Only water-based lubricants or appropriate spermicide should be used with latex (male) condoms. Oil-based lubricants, such as petroleum jelly, cooking oils, shortening, or lotions, results in a 90% reduction in latex strength in just 60 seconds and promote breakage. For latex condoms to be effective they should be stored in a cool, dry area, out of direct sunlight to prevent deterioration. Common errors in use include delaying condom application until just prior to full penetration, failure to extend the male condom all the way to the base of the penis, insufficient application of a water-based lubricant, and failure to hold the base of the condom during withdrawal. Finally it is essential to emphasize consistent condom use, with every sexual act.